4/7/2024 0 Comments Cremaster muscle injury![]() 41 Another study using this model demonstrated a critical role for α4 integrins during interleukin-4 (IL-4)-induced leukocyte recruitment (eosinophils and mononuclear cells) due to its ability to initiate leukocyte-endothelial cell interactions even in the absence of selectins under shear conditions in vivo. ![]() 40 IVM studies in the cremaster muscle of mice deficient for P-selectin identified a regulatory role for P-selectin in interleukin-13-induced leukocyte transmigration that was tissue specific. 38,39 These studies have led to the understanding of important aspects of leukocyte trafficking including slow rolling, intraluminal crawling, and pathways of transmigration. This model has been widely used to evaluate trafficking of leukocytes, particularly neutrophils, 35–37 and to some extent lymphocytes. The organized vascular network of the cremaster muscle is another alternative for the assessment of cell trafficking in vivo under flow conditions by IVM.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |